UPDATE 12.30pm: 

A 65-YEAR-OLD man who was involved in yesterday's crash at Apple Tree Creek is in a critical but stable condition in Hospital.

A spokesman for the Wide Bay Hospital and Health Service said the man had multiple traumas.

Three other patients were transported to Bundaberg Hospital in stable conditions.

The Bruce Hwy was reopened at about 8pm last night.

Wide Bay Forensic Crash Unit spent most of the day on scene yesterday and are continuing investigations.

EARLIER (Tuesday 2pm): 

A police media spokeswoman said the Bruce Highway will remain closed in both directions for the rest of the day. 

CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash.
CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash. 7News Wide Bay

UPDATE 11.25AM: 

WIDE Bay Forensic Crash Unit are on scene investigating the cause of the Apple Tree Creek crash.

Police spokesman has confirmed the highway will remain closed for an unknown period of time.

CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash.
CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash. 7News Wide Bay

EARLIER: 

THE Bruce Hwy is closed in both directions and is expected to stay closed for some time after a B-double truck has jack knifed and rolled across both the north and southbound lanes at Apple Tree Creek.

Two cars travelling north bound and a third car travelling south bound subsequently crashed into the rolled truck at 4.40am.

CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash.
CRASH: The Bruce Highway was closed at Apple Tree Creek after a multi-vehicle crash. 7News Wide Bay

Four patients were assessed by Queensland Ambulance Service.

A male patient in his 40s with a spinal injury, a male patient in his 40s with a knee injury and a male patient in his 50s with abdominal, back and pelvic injuries were transported to Bundaberg Hospital in stable conditions.

The truck driver did not require ambulance assistance.

The Chronicle understands there is a detour in place but motorists are advised to avoid the area.

MORE TO COME